Work: Universitats Klinikum Bonn – Institut fur Virologie, Bonn, Germany
The group’s research is dedicated to the ecology of viruses in their host- and dead end host contexts. We look for novel viruses in humans and animals and try to obtain estimates on their clinical relevance. We are interested in mechanisms of virus maintenance in reservoir hosts and in functional correlates of species barriers. We currently conduct field work in Ghana, Brazil, and several places in Europe. The search for new viruses requires a strong repertoire in molecular diagnostics, which is why we invest considerably in assay technologies. Here we have a strong interaction with our diagnostics section. In molecular biology we focus on coronavirus models. Our ongoing projects try to address mechanisms that determine the capability of viruses to switch hosts, and the prediction of the pathogenic potential of reservoir-borne coronaviruses.